When shipping medicines or gourmet food, you can’t afford temperature swings. FedEx cold chain solutions offer specialized packaging, state of the art facilities and around the clock monitoring so your products stay within required ranges from pickup to delivery. By leveraging a global network of cold chain centers and life science facilities, FedEx helps you comply with strict healthcare regulations and deliver on time. This guide breaks down how FedEx’s temperature controlled logistics work, por qué son importantes en 2025 and how you can use them to gain a competitive edge.
What are cold chain solutions and why are they critical in 2025? We look at market trends and regulations shaping temperature controlled logistics.
How does FedEx maintain precise temperatures? Discover the temperature ranges and intervention services offered by FedEx cold chain facilities.
Which FedEx facilities support cold chain shipments? Explore cold chain centers, life science centers and the global network of 90+ temperature controlled sites.
What technologies make FedEx cold chain services reliable? Learn how FedEx Surround®, AI enabled sensors and real time monitoring protect sensitive cargo.
How can your business benefit? Practical scenarios for healthcare, alimento, research and industrial sectors.
¿Qué hay de nuevo en 2025? Trends like DSCSA deadlines, FSMA 204 requisitos, automation and sustainability—and what they mean for you.
What Are FedEx Cold Chain Solutions and Why Do They Matter?
A growing need for cold chain logistics
Cold chain solutions maintain a precise temperature throughout the shipping journey, from manufacturer to end customer. They’re essential for vaccines, biológicos, clinical trial samples, comida gourmet, flowers and other perishable goods. As Asia Pacific’s appetite for fresh and frozen food grows, the cold chain logistics market in the region is expected to expand from USD 168.24 billion to Dólar estadounidense 253.92 mil millones por 2030. E commerce is also fueling demand; the food e commerce market in APAC could reach Dólar estadounidense 635.44 mil millones por 2029. While consumer expectations rise, regulatory pressures such as the Ley de seguridad de la cadena de suministro de medicamentos (DSCSA) y el Ley de modernización de la seguridad alimentaria (FSMA) 204 regla require companies to serialize prescription drugs and track key data elements—like location and temperature—within 24 horas.
Against this backdrop, businesses need reliable partners to ensure product integrity. FedEx cold chain solutions combine a global transportation network, specialized facilities and advanced technologies to address these demands. FedEx operates an integrated air and ground network that reaches over 220 countries and territories. y, a partir de 2024, manages a fleet of more than 680 aircraft and 200,000 vehículos.. This infrastructure underpins its cold chain capabilities.
FedEx’s role in the cold chain ecosystem
In FedEx terminology, Soluciones de cadena fría include temperature controlled packaging, cold chain centers, life science centers and monitoring services. These offerings ensure that shipments remain within specified temperature ranges. FedEx also provides compliance management, helping you meet Good Distribution Practice (PIB), DSCSA and FSMA requirements. By blending logistics expertise with healthcare industry knowledge, FedEx enables time critical deliveries while protecting product quality.
Understanding FedEx Temperature Ranges and Services
Temperature categories explained
FedEx supports multiple temperature ranges to accommodate different product needs. The cold chain centers feature three temperature controlled rooms:
Congelado: –10 °C to –25 °C (14 °F to –13 °F). Ideal para vacunas, biológicos y alimentos congelados.
Cold/Refrigerated: 2 °C a 8 °C (35 °F a 46 °F). Used for pharmaceuticals, dairy products and fresh produce.
Temperatura ambiente controlada (CRT): 15 °C a 25 °C (59 °F a 77 °F). Suitable for many medicines and laboratory reagents.
Some facilities offer deep frozen ranges down to –150 °C. for advanced therapies and cell gene products. Other locations, such as the Life Science Center in Mumbai, apoyo –80 °C almacenamiento..
Intervention services when things go wrong
Even the most carefully planned shipment can face delays from weather, customs or traffic. FedEx provides proactive intervention through FedEx Priority Alert Plus. At cold chain centers, the service includes re icing, gel pack replenishment and cold storage to protect shipments if delays occur. For more critical shipments, FedEx Surround® Premium ofertas 24/7 monitoring and will proactively replenish dry ice or gel packs if temperature thresholds are exceeded. This level of intervention helps prevent temperature excursions and ensures compliance.
Transport options tailored to your needs
Not every shipment needs the same speed. FedEx provides expedited air services for urgent healthcare products and more cost effective ground and less than truckload (LTL) services for non urgent goods. This flexibility allows shippers to balance delivery times, costs and temperature requirements.
Mesa: Temperature ranges and FedEx solutions
| Rango de temperatura (°C) | FedEx Solution Type | Practical Use Cases |
| –150 to –80 (Deep Frozen) | Life science centers (p.ej., deep frozen storage areas in Gimpo and Mumbai) | Celúla & terapias génicas, cryogenic materials.. |
| –25 to –10 (Congelado) | Cold chain centers and frozen shipping service | Vacunas, biológicos, alimentos congelados |
| 2 a 8 (Frío) | Refrigerated shipping; Life Science Centers | Insulina, lácteos, flores, diagnóstico. |
| 15 a 25 (Temperatura ambiente controlada) | Ambient shipping; Cold chain centers | Oral medicines, chemical reagents |
| Múltiples zonas (–150 to +25) | Upgraded Life Science Centers in Gimpo (2,288 m²) with five zones | End to end healthcare logistics requiring multiple temperature ranges. |
FedEx Facilities Supporting Cold Chain Shipments
Cold chain centers and global reach
FedEx cold chain centers are specialized facilities that maintain required temperatures during unforeseen delays. El Memphis Cold Chain Center, opened in 2016 at FedEx’s World Hub, sets the standard. It has dedicated rooms for frozen, cold and controlled room temperature shipments and provides real time carbon dioxide, humidity and temperature monitoring.. Staff are on site 24/7, with an International Document Agent (IDA) station to handle paperwork.. The facility offers dry ice replenishment, gel pack exchange, cross docking and a cold lock dual door design para un control preciso.. Smaller cold chain facilities are also located in Francia (Charles de Gaulle), Alemania (Cologne Bonn) y Japón (Kansai)..
According to FedEx’s 2024 Economic Impact Report, la empresa operates 90 cold chain facilities worldwide. El Miami cold chain facility, the largest in the network, spans 70,000 pies cuadrados con 12 pre cooled rooms that maintain temperatures from –13 °F to 77 °F. It includes an in house clearance facility that accelerates inspections, ensuring flowers and perishables arrive fresh. During Valentine’s Day, the facility processes 2.2 million pounds of flowers, demonstrating how scale and speed support seasonal peaks.
Life Science Centers: specialized healthcare hubs
FedEx also operates Life Science Centers—Good Supply Practice (SGP) certified facilities designed for clinical trials and pharmaceutical logistics. El Korea Life Science Center in Gimpo, expanded in November 2024, now spans 2,288 metros cuadrados—almost three times larger than before—and features five temperature controlled zones ranging from –150 °C to +25 °C, all monitored continuously.. This center supports both domestic and international shipments and meets Korea’s regulatory requirements. FedEx uses it as a showcase for end to end cold chain capabilities, as highlighted during the 3rd Korea Cold Chain exhibition en abril 2025..
En febrero 2024, FedEx opened a Life Science Center in Mumbai with comprehensive cold chain capabilities. The facility covers all three temperature zones—controlled ambient (15–25°C), refrigerado (2–8 ° C) and frozen/deep frozen (–20 °C a –80 °C)—and offers 24/7 monitoring and alarms.. It provides destruction services for returned investigational medicinal products, document storage, GCP/GDP compliance, gel pack and dry ice replenishment, backup power generators and secure packaging.. FedEx also offers Customized Freight y Priority Alert Plus™ services to manage these shipments, ensuring boarding priority, custodial control, and proactive monitoring..
FedEx operates Life Science Centers in Memphis (EE.UU), Bombay (India), Singapur, Tokyo (Japón) and Veldhoven (Países Bajos), forming a global network.. These hubs connect with more than 130 cold chain facilities worldwide, ensuring continuous temperature integrity for healthcare shipments..
Integrated air and ground network
FedEx’s cold chain capabilities are tightly integrated with its global air and ground network. El 2024 Economic Impact Report notes that the Miami International Airport serves as the Latin America and Caribbean (LAC) gateway with specialized cold chain capacity. Mientras tanto, Indianapolis hosts the second largest FedEx air hub, facilitating rapid transfers between air and ground transport. Such integration helps shippers reach international markets quickly while maintaining temperature control.
Technologies Powering FedEx Cold Chain Solutions
Real time monitoring and FedEx Surround®
Monitoring is at the heart of cold chain integrity. FedEx Surround® Premium proporciona 24/7 shipment visibility and proactive intervention. The system continuously monitors location, temperatura y humedad; when a shipment is at risk of exceeding its specified range, FedEx Surround can trigger dry ice replenishment or gel pack replacement. Priority treatment ensures that critical healthcare shipments receive top tier support.
AI enabled sensors and predictive analytics
Leading cold chain providers are adopting IoT sensors and AI to detect deviations before they compromise product quality. El Tempk industry report notes that UPS and FedEx use AI enabled sensors to spot and correct temperature deviations in real time. Predictive analytics can reroute shipments or adjust refrigeration setpoints to prevent excursions. FedEx’s scale—680 aircraft and 200,000 vehicles—allows it to capture vast amounts of data and apply machine learning for route optimization..
FedEx Clinical Care and Priority Alert services
FedEx offers dedicated services for healthcare shipments:
FedEx Clinical Care delivers investigational medicinal products, biological samples and medical kits with end to end control. It provides temperature controlled packaging, priority handling, y 24/7 monitoring and intervention.. Shipments are delivered within 24–48 horas to major cities..
FedEx Priority Alert™ and Priority Alert Plus™ provide premium boarding priority, real time tracking and personalized guidance in case of delays. Priority Alert Plus adds options such as dry ice replenishment, gel pack exchange and cold storage..
FedEx Customized Freight (FCF) is designed for critical pharmaceutical freight requiring custodial control, boarding priority, and dedicated first/last mile delivery..
Packaging innovations and compliance support
FedEx uses phase change materials (PCM), paneles de aislamiento al vacío (VIP), gel packs and dry ice to maintain specific temperatures. The company provides validated packaging and labeling solutions that comply with Good Clinical Practice (PCG), Buena práctica de distribución (PIB) y Ley de seguridad de la cadena de suministro de medicamentos (DSCSA) requisitos.. Proper documentation and electronic tracking help shippers meet DSCSA serialization deadlines (May–November 2025) y FSMA 204 reglas de trazabilidad.
Escenarios prácticos: How FedEx Cold Chain Solutions Benefit You
Productos farmacéuticos y biológicos.
Si envía vacunas, monoclonal antibodies or cell therapies, maintaining precise temperatures is non negotiable. FedEx’s frozen and deep frozen services support temperatures down to –150°C., ensuring product efficacy. 24/7 monitoring and intervention reduce the risk of temperature excursions, while GDP and DSCSA compliance help satisfy regulatory requirements.
Clinical trials and investigational medicinal products
Clinical trial logistics require chain of custody documentation, temperature integrity and quick turnaround. FedEx’s Life Science Centers offer secure storage, destruction services for returned IMPs, document archiving and GMP compliant labeling.. FedEx Clinical Care ensures that kits and samples are delivered within 24–48 horas., enabling time sensitive trial protocols.
Food and perishables
Productos frescos, flores, seafood and gourmet meals require consistent cooling. FedEx cold chain centers and refrigerated shipping options maintain 2–8 ° C for perishable goods. During seasonal peaks—like Valentine’s Day—the Miami facility processes 2.2 million pounds of flowers within 48–72 hours. Re icing and gel pack replenishment services preserve quality even during unexpected delays.
Research and industrial samples
Laboratories and industrial companies often ship reagents, enzymes or specialty chemicals at controlled room temperature (CRT). FedEx provides 15–25°C shipping options and CRT rooms in its cold chain centers.. With real time temperature monitoring, you can ensure that samples arrive viable for testing.
Small and medium enterprises (SMEs)
SMEs exporting fresh foods or specialty products may lack resources to build their own cold chain infrastructure. FedEx offers scalable solutions—from shared cold chain centers to cost effective ground transport. APAC SMEs can leverage FedEx’s network to tap into a Dólar estadounidense 253.92 mil millones market by 2030, and e commerce shipments can reach customers across the region quickly. FedEx also provides digital tools, como FedEx Surround, to monitor shipments and reduce wastage.
Key Trends and Regulations Shaping Cold Chain Logistics in 2025
DSCSA y FSMA 204 plazos
El A NOSOTROS. Ley de seguridad de la cadena de suministro de medicamentos (DSCSA) mandates serialization and electronic tracking of prescription drugs. Por Puede 27 2025, manufacturers must provide transaction data, wholesalers must verify saleable returns by Agosto 27 2025, and dispensers must accept only serialized products by Noviembre 27 2025. FedEx’s digital tracking systems and compliance support help shippers meet these deadlines.
El Ley de modernización de la seguridad alimentaria (FSMA) 204 regla extends traceability requirements to high risk foods. Companies must track key data elements—such as location, time and temperature—and supply records within 24 horas. Choosing a partner like FedEx, which uses IoT sensors and real time monitoring, simplifica el cumplimiento.
Other regulatory frameworks
Buena práctica de distribución (PIB): Outlines quality management, equipment qualification, temperature mapping and documentation requirements.
Análisis de riesgos y puntos de control críticos (HACCP) y Normas ISO: Require identification of critical control points and robust quality management systems.
Working with providers that comply with these frameworks reduces the risk of product loss and regulatory violations.
Technology trends
IoT and real time visibility: Wider adoption of IoT sensors and cloud platforms provides continuous visibility and predictive insights.
IA y análisis predictivo: AI models forecast demand, optimize routes and anticipate maintenance needs.
Blockchain para la trazabilidad: Immutable ledgers streamline audits and build trust. FedEx and DHL are experimenting with blockchain pilots for cross border shipments.
Sostenibilidad: Companies install solar panels, adopt low global warming potential refrigerants and use energy efficient refrigeration. FedEx is pursuing carbon neutral operations by 2040.
Embalaje avanzado: Materiales de cambio de fase (PCM), paneles de aislamiento al vacío (VIP) and smart packaging extend transit times while reducing reliance on dry ice.
Automatización y robótica.: Automated warehouses improve throughput and reduce energy consumption.
E commerce and last mile delivery: Growing online grocery shopping increases demand for refrigerated delivery vans and micro fulfilment centers.
Resilience and risk mitigation: Diversification of suppliers, dynamic route planning and scenario modeling help address climate and geopolitical risks.
Latest Developments at FedEx (2024–2025)
FedEx continues to invest in its cold chain network:
Expanded Life Science Center in Gimpo, Korea (Noviembre 2024) – FedEx nearly tripled the size of its Gimpo facility to 2,288 m² and introduced five temperature zones (–150 °C to +25 °C).. Continuo 24/7 monitoring ensures pharmaceutical compliance. The facility was showcased during the 3rd Korea Cold Chain exhibition en abril 2025..
Life Science Center in Mumbai (Febrero 2024) – FedEx opened a new center covering all three temperature zones and added features like destruction services, document archiving, GCP/GDP compliance y backup power generators.. FedEx delivers healthcare shipments across more than 6,000 postal codes in India within 24–48 hours..
Recognition for innovation (2024) – FedEx received the Innovation in Clinical Supply Chain Logistics award at the Korea Biopharma Excellence Awards, highlighting its use of advanced technologies and global expertise.. FedEx also won awards for logistics and last mile implementation..
Miami cold chain facility spotlight (2024 informe) - El 70,000 square foot Miami facility remains the largest in the FedEx network, con 12 pre cooled rooms and an in house clearance capability. It processes 2.2 million pounds of flowers during Valentine’s Day and demonstrates FedEx’s ability to handle seasonal peaks.
Network 2.0 y transformación digital – FedEx is consolidating its operating companies into a single entity and optimizing its physical network. The company uses AI and machine learning to digitize supply chains and introduced fdx, a data driven e commerce platform. These innovations make cold chain logistics smarter and more efficient.
Tips for Businesses Using FedEx Cold Chain Services
Choosing the right service
Evalúe su producto: Determine the temperature sensitivity and required range. For biologics needing –80 °C or below, choose a life science center. For vaccines or perishable foods, use cold chain centers or refrigerated shipping.
Planifique con anticipación: Reserve capacity at life science centers early, Especialmente durante las temporadas pico (p.ej., holidays or flu season). Provide accurate shipment data for customs clearance.
Use monitoring tools: Enroll in FedEx Surround Premium or Priority Alert to receive real time alerts and proactive intervention.
Verify compliance: Ensure that packaging meets GDP, DSCSA and FSMA requirements. Work with FedEx to document chain of custody and temperature data.
Leverage sustainability: Ask your FedEx representative about renewable energy projects and carbon neutral shipping options. Sustainable practices can improve brand reputation.
Ejemplo de caso: A biotech startup shipped a gene therapy that required –80 °C storage from Mumbai to San Francisco. By using the Mumbai Life Science Center’s deep frozen zone and enrolling in FedEx Surround, the company maintained temperature integrity throughout transit. Sensors alerted the operations team when dry ice was running low, and replenishment occurred mid journey, preventing any deviation. The shipment arrived within 48 horas, enabling the clinical trial to proceed on schedule..
2025 Trends and Market Insights
Descripción general de la tendencia: The cold chain industry is experiencing rapid technological and regulatory change. IoT and AI are improving visibility and predictive power, while blockchain offers tamper proof documentation. Sustainability and energy efficiency are no longer optional; companies deploy solar panels, LED lighting and low GWP refrigerants. Automation is reducing labor and improving space utilization, and e commerce is driving demand for last mile cold storage. Regulation is tightening, with DSCSA and FSMA 204 deadlines requiring digital traceability. North America still dominates refrigerated warehousing with a 37.7% cuota de mercado but Asia Pacific is the fastest growing region.
Últimos desarrollos de un vistazo
NewCold’s automated warehouse in Poland (Septiembre 2025) adds 95,000 pallet positions and emphasizes energy efficiency. This facility exemplifies the industry’s push toward automation.
Americold’s sustainability investments (2024) generado 22 million kWh in energy savings and enrolled 213 facilities in the GCCA Energy Excellence program.
Lineage’s solar capacity alcanzó 108 MW in 2024, ranking it fifth among U.S. corporate solar users.
These developments illustrate how leading cold chain providers are investing in automation, renewable energy and expansion into high growth markets.
Preguntas frecuentes
What is a cold chain solution?
A cold chain solution maintains a specific temperature range throughout the supply chain to preserve product quality. For FedEx, this includes packaging, transporte, storage and 24/7 monitoring at specialized facilities.
How does FedEx comply with the DSCSA 2025 plazos?
FedEx uses electronic tracking and serialization tools so that manufacturers, wholesalers and dispensers can capture and verify transaction data. It helps customers prepare for the DSCSA milestones in May, agosto y noviembre 2025.
Can I ship vaccines or clinical trial samples through FedEx?
Sí. FedEx Life Science Centers support frozen and deep frozen shipments and offer services like destruction of unused investigational medicinal products, document archiving and GCP/GDP compliance.. FedEx Clinical Care ensures delivery within 24–48 hours..
What is FedEx Surround® and why should I use it?
FedEx Surround Premium provides 24/7 visibility and proactive intervention for high value shipments. If a package approaches its temperature limit, FedEx re ices or adds gel packs and prioritizes the shipment.
What packaging options are available?
FedEx offers insulated boxes with gel packs, hielo seco, phase change materials and vacuum insulation panels. Packaging is validated to meet GDP and DSCSA requirements..
How does FedEx support sustainability?
FedEx is investing in renewable energy, electrification of its fleet and energy efficient facilities. The company aims to achieve carbon neutral operations by 2040. Paneles solares, low GWP refrigerants and automation contribute to this goal.
Resumen y recomendaciones
FedEx cold chain solutions give you a robust platform for shipping temperature sensitive goods. By leveraging a global network of 90+ cold chain facilities and specialized Life Science Centers, FedEx maintains temperatures from –150 °C to +25 °C. Intervention services like re icing, gel pack replenishment y dry ice replacement ensure that shipments remain within range. Tecnologías de monitoreo avanzadas, incluido FedEx Surround, AI enabled sensors y visibilidad en tiempo real, allow proactive management. With compliance support for DSCSA, FSMA and GDP, FedEx helps you navigate an increasingly regulated environment. Si está enviando vacunas, gourmet food or clinical trial samples, FedEx offers scalable solutions tailored to your needs.
Próximos pasos viables
Evalúe sus requisitos de temperatura – Identify the appropriate range and choose between cold chain centers or life science facilities. Use FedEx’s planning tools or consult a representative.
Enroll in monitoring services – Opt for FedEx Surround Premium or Priority Alert to receive real time alerts and intervention.
Prepare for DSCSA and FSMA compliance – Work with FedEx to integrate serialization and traceability data into your supply chain.
Considere la sostenibilidad – Ask about carbon neutral shipping options and packaging with recyclable materials.
Leverage digital tools – Utilize FedEx’s AI driven platforms to optimize routes, reduce delays and improve customer satisfaction.
Acerca de Tempk
Tempk is a company specializing in temperature controlled packaging and cold chain solutions. Combinamos la investigación, engineering and eco friendly design to develop insulated boxes, gel packs and other cooling products that help businesses maintain product integrity during transit. Our expertise spans industries—from pharmaceuticals to gourmet foods. We prioritize sustainability by offering reusable and recyclable options and hold multiple certifications, including Sedex and Good Manufacturing Practice (BPF). Nuestra R&D team works with clients to customize packaging that balances performance and cost, making us a trusted partner for cold chain logistics.
Llamado a la acción: If you’re looking for tailored cold chain solutions or need advice on packaging and compliance, Póngase en contacto con los especialistas de Tempk hoy. We’re ready to help you optimize your supply chain and protect your sensitive shipments.
