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Bolsa de hielo seco & Pack Sheet Guide for Safe Cold Chain Logistics

Dry ice pack sheets are revolutionizing cold chain logistics. A diferencia del hielo seco tradicional, these flexible sheets use phase change materials (PCM) to maintain ultra low temperatures between –20 °C and –70 °C for up to 72 horas. They activate when flexed and don’t sublimate into carbon dioxide gas, making them easier to handle and comply with regulations. Para cargadores, understanding how to select and use these sheets—along with conventional bolsas de hielo secas—can reduce spoilage, cut costs and ensure safety. This guide explains their benefits, usage guidelines and trends so you can ship with confidence.

Bolsa de hielo seco

What is a dry ice bag and how does it differ from a dry ice pack sheet? — definitions, temperature range and handling implications.

How do dry ice pack sheets improve coldchain logistics? — benefits, seguridad, sustainability and regulatory advantages.

How to package and use dry ice safely? — stepbystep instructions for both traditional dry ice and modern pack sheets, including training requirements, labeling and venting.

How much dry ice do you need? — ruleofthumb quantities and simple calculations to ensure your shipment stays cold without overloading.

What’s new in coldchain technology for 2025? — insights on smart monitoring, hybrid cooling systems and market trends.

Preguntas frecuentes — clear answers about duration, reutilizar, disposal and international shipping.

What are dry ice bags and pack sheets, and why do they matter?

Dry ice bags are traditional blocks or pellets of solid carbondioxide packaged in breathable bags. They keep products frozen by absorbing heat and sublimating directly to CO₂ gas at –78.5 °C. Each pound of dry ice delivers more than twice the cooling energy of water ice, but the gas buildup can cause pressure, create an oxygendeficient atmosphere and require special handling. These bags must be vented, labeled as “Carbon Dioxide, Sólido" (Y 1845) and used by trained personnel.

Dry ice pack sheets are flexible thermal devices containing proprietary PCMs that freeze at ultralow temperatures. When flexed before use, the PCMs start absorbing heat and release cold energy for 24–72 hours. Because pack sheets do not sublimate or emit hazardous gases, they are classified as nonhazardous. This simplifies documentation, reduces training requirements and eliminates the need for vented packaging. Pack sheets are particularly useful for overnight shipments, emergency deliveries and crossborder logistics.

How dry ice pack sheets work

Dry ice pack sheets function like miniature cold batteries. Each sheet contains a calibrated PCM that shifts from solid to liquid within a targeted range (–20 °C a –70 °C). During phase change, the material absorbs large amounts of heat, keeping products ultracold without freezing them. Unlike solid CO₂, the PCM doesn’t sublimate, so there is no release of gas, and the cold energy remains stable. Users simply flex the sheet to activate the PCM and insert it into the insulated container, where it begins cooling immediately.

Característica Traditional dry ice bag Hoja de hielo seco Lo que significa para ti
Rango de temperatura Maintains –78.5 °C; extremely cold Maintains –20 °C to –70 °C for 24–72 hours Pack sheets provide precise ultracold temperatures without excessive freezing, ideal for biologics or delicate specimens.
Cooling energy More than twice the cooling energy of water ice per pound High energy density due to PCM; consistent output Both offer strong cooling, but pack sheets deliver uniform cold without CO₂ release.
Manejo & seguridad Requires insulated gloves; frostbite risk and hazard classification (Clase 9) Classified as nonhazardous; no frostbite risk, requires standard thermal gloves Pack sheets reduce training costs and injury risk.
Cumplimiento regulatorio Debe ser ventilado; labeled “Carbon Dioxide, Solid” and UN 1845; quantity limit 200 kg por paquete Simplified documentation; complies with most international regulations without hazmat declarations Pack sheets streamline customs and carrier approvals.
Duración & reutilizar Sublimates at 5–10 lbs per 24 horas; cannot be reused Lasts 24–72 hours depending on model; many versions are reusable for 50+ ciclos Pack sheets provide longer cold time and can be refrozen, Reducción de costos.
Impacto ambiental Made from CO₂; releases gas; packaging often singleuse PCMs can be produced from renewable CO₂ and enclosed in recyclable materials Choosing sustainable pack sheets reduces waste and carbon footprint.

Consejos prácticos y sugerencias.

For highvalue biologics: Use dry ice pack sheets to maintain the required –20 °C to –70 °C range without subjecting your product to –78.5 °C. The absence of CO₂ gas simplifies international shipping.

For large frozen goods: Traditional dry ice bags provide more cooling energy per pound; sin embargo, ensure the container is vented and labeled correctly to meet regulatory requirements.

Para envíos mixtos: Combine dry ice bags with gel packs or pack sheets to balance ultracold temperatures and avoid freezing goods like fresh seafood or pharmaceuticals sensitive to freezing.

Real world example: A celltherapy manufacturer needed to ship doses requiring –40 °C overnight across the country. By switching from bulky dry ice blocks to pack sheets, the team avoided hazardous materials paperwork and simplified handling. The pack sheets maintained the precise temperature for 48 hours and reduced handling costs by 25 %, demonstrating how modern refrigeration technologies optimize coldchain logistics.

Packaging and usage guidelines

Training and hazard identification

Dry ice is classified as a “miscellaneous” hazard (Clase 9) by both the U.S. Departamento de Transporte (PUNTO) y la Asociación Internacional de Transporte Aéreo (IATA). Shipments that include only dry ice require hazardous materials training; employees must be certified before packaging or signing shipping documents. Training must be renewed every two years because regulations change frequently.

The main hazards associated with dry ice are:

Explosion hazard: Sublimating CO₂ gas can build pressure in sealed containers, potentially causing an explosion.

Suffocation hazard: In confined spaces, CO₂ gas can displace oxygen and create an oxygendeficient atmosphere.

Contact hazard: Dry ice causes severe frostbite upon direct contact with skin. Always wear insulated gloves when handling blocks or pellets.

Dry ice pack sheets do not carry these risks because the PCM does not sublimate. Standard thermal gloves are recommended to avoid cold burns.

Requisitos de embalaje

When shipping with traditional dry ice bags, follow these regulations:

Gas venting: Packages must allow the release of carbondioxide gas; nunca selle el hielo seco en un recipiente hermético, threaded lid or sealed plastic bag.

Package strength: Containers must be insulated, free from damage and strong enough to withstand normal loading and unloading, vibration and changes in temperature, humidity and altitude.

Material choice: Avoid plastics that become brittle at dryice temperatures; use commercially available dryice shipping systems.

Etiquetado: The outer container must display the Class 9 etiqueta de peligro, "Dióxido de carbono, Sólido,” the UN 1845 identifier and the net weight of dry ice in kilograms. Labels should be affixed to a vertical side of the box and oriented upright.

Documentación: The air waybill must state “UN1845, Hielo seco, number of packages × net weight in kilograms.” FedEx and other carriers provide check boxes on their airbills to satisfy this requirement.

Límites de cantidad: The maximum net quantity of dry ice per package is 200 kilos. Some carriers impose additional limits (p.ej., UPS restricts uncontracted shipments to 2.5 kg without a hazardous materials agreement).

Carrier restrictions: FedEx and DHL accept dryice shipments, but UPS and the U.S. Postal Service restrict hazardous materials; consult your carrier before shipping. Always coordinate logistics with the recipient and consider holidays or local closings to avoid delays.

For dry ice pack sheets, packaging is simpler:

Use insulated containers (p.ej., EPS, vacuum panels or rigid coolers) Para minimizar la transferencia de calor.

Seal the container to prevent moisture ingress but include a small vent if recommended by the sheet manufacturer.

Add secondary packaging and cushioning to secure the product, just as you would for dry ice shipments.

Handling procedures

The following steps outline proper handling for both dry ice bags and pack sheets:

Prepare the container: Choose an insulated box with minimal dead space. Fill any open areas with wadded paper or foam to reduce the rate of sublimation.

Place the refrigerant: For dry ice bags, place them on top of or around the product, not inside sealed primary receptacles. For pack sheets, flex the sheet to activate the PCM, then line the container walls or wrap the product directly.

Add cushioning: Secure secondary packaging so that it maintains orientation after the refrigerant melts or warms. Use cardboard or bubble wrap to immobilize fragile items.

Sello y etiqueta: Close the insulated container, tape only the center seam of the outer box, affix hazard labels if using dry ice bags, and mark the net weight of dry ice.

Complete documentation: Fill out the air waybill with the UN 1845 details and note the number of packages. Provide training certificates if requested.

Arrange pickup and delivery: Schedule expedited services (overnight or priority) to ensure goods arrive within the refrigerant’s effective duration. Inform the recipient of the expected arrival date and ensure they can unpack promptly.

Packing for specific goods

Frozen foods and meats: Use heavy dry ice bags combined with gel packs to maintain frozen temperatures. According to shipping tables, a 10 lb product requires 10–15 lb of dry ice to maintain cold for 24–48 hours. For long distances, consider pack sheets to extend cooling and reduce hazardous materials paperwork.

Pharmaceuticals and vaccines: Regulatory bodies require that injectable medicines remain between 2–8 °C. Cold packs can achieve this range; avoid dry ice unless the product can withstand freezing. Pack sheets designed for moderate temperatures (–20 °C to –40 °C) offer an alternative for biologics needing ultracold storage without the hazards of CO₂.

Cell and gene therapies: These treatments often require –50 °C or colder. Pack sheets maintain –20 °C to –70 °C and can be combined with small amounts of dry ice to extend duration and maintain regulatory compliance.

Safety considerations and compliance

Equipo de protección personal

For traditional dry ice, wear leather or cryogenic gloves to prevent frostbite. Cover exposed skin with long sleeves and pants, and use safety glasses or a face shield when breaking blocks. Only handle dry ice in wellventilated areas to avoid CO₂ accumulation.

Dry ice pack sheets require less PPE. Standard thermal gloves are sufficient to prevent cold burns, and there is no risk of gas buildup.

Storage and disposal

Store dry ice in a hardsided insulated container; thicker insulation slows sublimation. Do not store in airtight or unventilated spaces such as refrigerators or closed vehicles. Fill open space with paper to limit dead air. Dispose of unused dry ice by leaving it in a wellventilated area or fume hood where it can sublimate safely.

Because pack sheets do not produce CO₂ gas, disposal is simpler. Many manufacturers offer recycling programs. Follow local regulations for PCM disposal.

Regulatory compliance checklist

Use this checklist to ensure compliance when shipping with dry ice bags:

Y 1845 declaration: Confirm that “Carbon Dioxide, Solid” and the UN number appear on both the air waybill and the package.

Etiqueta de peligro: Ajuste la clase 9 miscellaneous hazard label on a vertical side of the box.

Peso neto: Mark the net weight of dry ice in kilograms. Do not exceed 200 kg por paquete.

Ventilación: Ensure the container allows CO₂ to escape; avoid airtight seals.

Training certification: Keep hazardous materials training documentation current.

Carrier restrictions: Verify that your carrier accepts dry ice shipments and whether a hazardous materials contract is required.

Pack sheets generally require none of the above except proper packaging and labeling of the product itself.

How much dry ice do you need?

Estimating how much dry ice to use depends on the payload weight, desired transit time and insulation level. Guidelines from universities and carriers provide a rule of thumb: dry ice sublimates at approximately 5–10 pounds per 24 horas. More insulation and less headspace slow the sublimation rate.

General calculation

Determine the weight of your product (carga útil).

Identify the required transit time (24, 48 o 72 horas).

Multiply the transit time by 5–10 lb to estimate the needed dry ice. Use the higher end for longer transit or less insulated containers. Por ejemplo, a 10 lb payload shipped for 48 hours might require 10–15 lb of dry ice.

Always consult your package manufacturer or carrier guidelines. Some carriers require shippers to include enough dry ice for an additional 24 hours to account for delays.

Weight guideline table

Payload weight Tiempo de tránsito Recommended dry ice weight Significado práctico
2 lb 12–24 horas 2–5 lb Small packages (p.ej., kits de comida) need modest dry ice; consider pack sheets for improved handling.
5 lb 24–48 horas 4–8 lb Suitable for medium frozen food shipments; ensure container is vented.
10 lb 24–48 horas 10–15 lb For larger parcels; consider combining dry ice and pack sheets for extended cooling.
20 lb 24–48 horas 15–25 lb Heavy shipments require substantial dry ice; training and labeling are critical.
50 lb 24–48 horas 20–30 lb Industrial or bulk shipments should follow formal hazardous materials protocols.

Always minimize air space and choose insulated containers to maximize efficiency. If using pack sheets, follow manufacturer instructions and consider stacking multiple sheets for longer durations.

Benefits of dry ice pack sheets vs traditional dry ice

Simplified compliance: Since pack sheets are nonhazardous and do not emit CO₂, they avoid hazardous materials training and labeling requirements.

Duración extendida: Highperformance pack sheets can maintain temperatures from –20 °C to –70 °C for up to 72 horas, outlasting many dry ice shipments.

Reutilizabilidad: Many pack sheet versions can be refrozen and reused for 50 + ciclos, providing longterm cost savings.

Safety and ease of handling: Pack sheets eliminate frostbite risk and require only standard thermal gloves. There is no explosion or suffocation hazard, and the sheets can be cut to size or wrapped directly around the product.

Sostenibilidad: Manufacturers are adopting renewable CO₂ sources and biodegradable or recyclable materials. Pack sheets therefore reduce the carbon footprint and support circular economy models.

Implementing dry ice pack sheets: paso a paso

Evalúa tus necesidades: Determine the required temperature range and duration for your shipment. Pack sheets cover –20 °C to –70 °C; choose a model that matches your product requirements.

Select appropriate packaging: Use insulated containers with minimal headspace. Pair pack sheets with vented packaging to ensure any incidental gas release can escape, even though PCMs themselves do not produce gas.

Activate the sheets: Flex each sheet gently until you feel the PCM crackle; this triggers the phase change, ensuring the sheet begins cooling immediately.

Position strategically: Line the interior walls of the container with pack sheets or wrap them around the product. For multiday shipments, layer multiple sheets or combine with small amounts of dry ice for extended duration.

Temperatura de monitor: Use temperature and humidity data loggers or integrated IoT sensors to track conditions during transit. Smart monitoring systems improve visibility and compliance.

Plan de reutilización: Después de la entrega, instruct recipients to refreeze and return pack sheets for future use. Implement takeback programs or recycling partnerships with manufacturers.

User tips and scenarios

Laboratory samples: Use multiple thin pack sheets to wrap around vials, then insert them into a padded, contenedor aislado. The uniform cold prevents freezethaw cycles that can damage samples.

Mealkit delivery: Combine a moderate dry ice bag with pack sheets to keep ingredients frozen yet avoid freezer burn. Place the pack sheet between the bag and the product to create a thermal buffer.

International shipments: Pack sheets simplify customs because they are nonhazardous. Always verify destination country regulations and include translation labels if needed.

2025 cold chain trends and innovations

The coldchain industry is rapidly evolving. En 2025, several trends are reshaping how businesses manage temperaturesensitive shipments:

Smart monitoring systems: Integrating IoT sensors into packaging allows realtime tracking of temperature and humidity. These sensors send data to cloud platforms, enabling proactive intervention if conditions deviate from set parameters. Visibility reduces spoilage and improves regulatory compliance.

Sistemas de enfriamiento híbrido: Combining dry ice with PCMs creates more stable temperature profiles and improves energy efficiency. Hybrid systems smooth temperature fluctuations and extend cooling duration.

Automation in packaging: Robotics and automated equipment are increasingly used to pack and handle refrigerants. Automation reduces human error, speeds up operations and ensures consistent packaging quality.

Materiales sostenibles: Biodegradable and recyclable packaging is becoming standard. Companies are exploring renewable CO₂ sources and recyclable insulation to reduce environmental impact.

Advanced material science: New PCM formulations extend the range of temperatures and duration of pack sheets. Some contain integrated sensors that transmit realtime data to logistics platforms.

Circular economy models: Manufacturers are implementing refurbishment and recycling programs for thermal materials. This reduces waste and lowers longterm costs.

Market growth: Demand for nextday dry ice pack sheets is projected to grow by about 20 % anualmente a través de 2026. Integrated digital platforms that combine monitoring, route optimization and predictive analytics are becoming essential to stay competitive.

Trend impact table

Tendencia Descripción How it helps you
Monitoreo inteligente IoT sensors track temperature and humidity in real time Improves compliance, reduces spoilage and provides endtoend visibility
Sistemas de enfriamiento híbrido Combining dry ice and PCMs stabilizes temperatures Extends cooling duration and reduces energy use
Automatización Robotic packing and handling systems Reduces human error and increases throughput
Materiales sostenibles Use biodegradable and recycled packaging Lowers environmental impact and appeals to ecoconscious consumers
Advanced PCMs New formulations broaden temperature ranges Provide flexibility for varied shipments
Integrated sensors Builtin monitoring systems send data to your platform Enables proactive response to deviations
Circular economy Takeback and refurbishing programs Reduce waste and save costs

Ideas del mercado

Coldchain logistics is expanding rapidly. Market analysis predicts that demand for nextday dry ice pack sheets will grow by roughly 20 % per year through 2026. As ecommerce, pharmaceuticals and biotechnology continue to boom, companies that adopt smart monitoring, sustainable materials and automation will see reduced spoilage, improved compliance and greater customer satisfaction. Staying ahead of these trends ensures your operations remain competitive.

Preguntas frecuentes

Q1: How long do dry ice pack sheets maintain temperature? Most dry ice pack sheets maintain their target temperature range for 24–48 hours, and highperformance versions can last up to 72 hours when paired with proper insulation. Always check manufacturer specifications and consider adding extra sheets for longer transit times.

Q2: Are dry ice pack sheets reusable? Sí. Many pack sheet models are reusable and can be refrozen for 50 + ciclos. This reusability reduces longterm costs and waste.

Q3: What safety precautions should I take when handling these sheets? Use standard thermal gloves and avoid direct skin contact. Ensure adequate ventilation when unpacking packages to avoid any coldinduced condensation.

Q4: Can dry ice pack sheets be used internationally? Sí. Because they are classified as nonhazardous, dry ice pack sheets comply with most international shipping regulations. Always verify countryspecific requirements and include translated labels if necessary.

Q5: How should I dispose of or recycle used pack sheets? Many manufacturers offer recycling programs. Follow local regulations for PCM disposal, or return the sheets to suppliers who refurbish them as part of circular economy initiatives.

Resumen y recomendaciones

Control de llave

Understand your refrigerant options: Traditional dry ice bags provide extremely cold temperatures but require strict handling, ventilation and labeling. Dry ice pack sheets offer flexible, nonhazardous cooling between –20 °C and –70 °C for up to 72 horas.

Follow packaging and safety guidelines: Paquetes de ventilación, use insulated containers and label shipments properly. Wear appropriate gloves and avoid confined storage.

Calcule sus necesidades de hielo seco: Use the rule of 5–10 lb of dry ice per 24 hours and consider hybrid solutions like pack sheets to extend duration and reduce weight.

Embrace emerging technologies: Monitoreo inteligente, hybrid cooling systems, automation and sustainable materials will define coldchain logistics in 2025.

Plan for sustainability: Choose products made from renewable CO₂, participate in takeback programs and reuse pack sheets to reduce your carbon footprint.

Actionable steps

Evaluate your coldchain needs: Determine temperature ranges, durations and regulatory requirements before selecting a refrigerant.

Develop standardized procedures: Create stepbystep guides for packing, labeling and documenting shipments. Ensure staff receive regular training on hazardous materials handling.

Invest in sustainable solutions: Opt for pack sheets and packaging made with recyclable materials and renewable CO₂ sources. Implement reuse and recycling programs.

Adopt smart monitoring: Use IoT sensors to track shipments in real time and respond quickly to temperature deviations.

Mantente informado: Monitor regulatory changes, carrier policies and market trends to maintain compliance and remain competitive.

Acerca de Tempk

Tempk is a pioneer in coldchain logistics, specializing in innovative dry ice pack sheets, gel packs and insulated containers. Our products are engineered to deliver consistent ultracold temperatures while prioritizing safety, sustainability and efficiency. We incorporate smart monitoring systems, ecofriendly materials and advanced PCM technology to help businesses protect highvalue biologics, foods and pharmaceuticals. With years of industry experience, Tempk provides customized solutions, expert guidance and ongoing support to optimize your coldchain operations.

Llamado a la acción: Ready to enhance your coldchain strategy? Consult Tempk specialists to select the right combination of dry ice pack sheets and packaging supplies for your shipments. Juntos, we’ll help you achieve safer, more sustainable and costeffective logistics.

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